
产品货号:
Z11416
中文名称:
AVEN抗体
英文名称:
Anti-AVEN Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AVEN Antibody |
指标别名 | AVEN;Cell death regulator Aven;PDCD12 |
克隆性 | Polyclonal |
检验物种 | human,monkey |
应用范围 | WB |
基因名称 | AVEN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from the C-terminal region of human Aven.at AA rangle:270-350 |
计算分子量 | 39KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells.Disruption of this process has been implicated in a variety of diseases such as cancer.Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9.It is thought that Aven functions by binding to Bcl-xL,an antiapoptotic member of the Bcl-2 family,and to Apaf-1,possibly interfering with the ability of Apaf-1 to self-associate,suggesting that Aven impedes Apaf-1-mediated caspase activation.Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients,suggesting that Aven may be useful as a prognostic indicator in leukemia patients. |
Uniprot ID | Q9NQS1 |
基因名全称 | Cell death regulator Aven |
推荐稀释比 | WB,1:500~1:2000 |
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